While we all experience periodic "mood swings," the symptoms of depression are a true partnership outlined by the American Psychiatric Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). According to the Diagnostic and Statistical Manual of Mental Disorders, at least 5 of 8 following symptoms must be present for at least one month in order to diagnose clinical depression:
- Weight loss due to lack of appetite, or accompanied by excess weight gain
- Frequent insomnia or hypersomnia (sleeping too much)
- Lack of interest in regular activities and / or a decrease in sexual behaviour
- In general feeling of fatigue
- Too much activity or inactivity
- Feelings of worthlessness or guilt
- Difficulty concentrating
- Thoughts of suicide
Anti-depressive drugs are an all-too frequent course of treatment for depression, but are not necessarily the best. On the one hand, there is a high rate of relapse and dependency associated with these drugs. An alternative is gaining popularity cognitive therapy used to manipulate brain chemistry by empowering the patient with the new "tools" for daily life. Indeed, cognitive therapy teaches the depressed person to replace the automatic negative thoughts with more appropriate. This process re-engineering of thought not only relieves the feeling of impotence or loss of control in the patient, but actually results in stabilizing brain chemistry.
Depression has a variety of causes, both physiological and organic origin. Some of the most recognized are: food allergies, hypoglycemia, hypothyroidism, diabetes, heart disease, environmental toxins (heavy metals), poor adrenal function, nutritional deficiencies and even certain medications. From this list is so long, it is important to seek help from a qualified health professional to rule out any of these conditions. Severe or major depression (especially when the thoughts of death or suicide are in sight) consists of a range of therapies and should only be treated by a qualified professional. However, mild to moderate depression can show improvement through the use of certain botanical products and nutritional considerations. However, you should discuss these therapies with their doctor first. It is also imperative that you never herbal medicines are combined with other anti-depressants prescription drugs.
Uncle Sam collects SAM
SAM (S-Adenosyl-methionine) is involved in the operation of monoaminas (such as serotonin, dopamine and gamma-amino butyric acid or GAB), neurotransmitters and some lipids. In "normal" brain chemistry, sufficient quantities of SAM are produced by the amino acid methionine, but this synthesis is altered in depressed people. Many double-blind, placebo-controlled studies have found Sam to be one of the most effective natural anti-depressants and is better tolerated and works faster than many tricylic anti-depressant drugs. Although SAM has been widely used in Europe for at least 20 years old, has only come to the U.S. in recent months.
The usual dose is 400 mg four times a day, but since SAM can cause nausea and vomiting that sometimes started at 200 mg twice daily for several days and gradually increased to full therapeutic dose. Note: the administration of supplements SAM is unsuitable for manic (bipolar) depression patients and their manic symptoms can be lifted.
St. John's Wort (Hypericum perforatum)
There are at least 10 pharmacologically active substances found in the extract of this plant, but researchers are most interested in hypericin and pseudohypericin. The exact mechanism of the herb's capacity to alleviate depression and anxiety remain largely unknown, but a recent study may provide some clues. The action of hypericin to sites alpha receptors, known to be involved in the role of MAOs and 5-HTP reuptake inhibitors (a metabolite of L-tryptophan in the synthesis of serotonin), supports the herb as a universal reputation a lift and humor sedative. The extract (standardized to 0.3%) is usually given at 300 mg three times a day with meals. Note: This herb can sometimes cause mild stomach irritation. Hypericin may also increase photosensitivity and has recently been linked with the formation of cataracts with long-term use.
Kava (Piper methysticum)
This herb has a long history of use in reducing anxiety, but is relatively new in the treatment of anxiety associated with depression. Several European countries have approved kava for treating insomnia, nervous disorders and depression. In the U.S., kava preparations are available as dietary supplements. Officials beneficial kava kavalactones found in the dried rhizome of the plant. Several studies have shown that the effects of kava a receiver Gabe-binding capacity and capability of blocking the absorption of norepinephrine. In 1997 a German study, 101 subjects who suffer from non-psychotic anxiety took part in a 25 week placebo-controlled, double-blind test with an extract of kava. The researchers concluded that kava is comparable to treatment with benzodiazepines, but without undesirable side effects. The recommended dose (30-70% to standardized) 45-70 mg three times a day.
Nutrition Guide
L-tryptophan is the metabolic precursor of melatonin and serotonin neurotransmitters with sedative qualities and useful in treating the symptoms of depression. However, L-tryptophan was banned in the U.S. due to an incidence of pollution and the Food and Drug Administration is unlikely to allow back into the market in the short term. However, a new supplement available, 5-hydroxytryptamine (5-HTP), may be even more effective. Unlike L-tryptophan, 5-HTP is readily bioavailable, as it does not require a molecule transport or compete with other amino acids in the system. While it is necessary to take into L-tryptophan on an empty stomach, 5-HTP can be taken with meals. In addition, 5-HTP is biochemically closer to serotonin, chemically known as 5-hydroxy tryptamine. Studies have also shown that 5-HTP increases beta-endorphins, the "feel good" hormones. The usual dose is 200 mg. per day.
According to the American Journal of Clinical Nutrition, there is a clear association between depression and a diet lacking in sufficient fatty acids, particularly omega-3. The brain depends on the membrane fatty acids to ensure the fluidity and function of nerve cells, the factors that effect neurotransmitter synthesis and transmission. Low omega-3 levels also influence the actions of monomine oxidase, the enzyme responsible for the breakdown of serotonin, dopamine and epinephrine. The best sources of omega-fatty acids are cold water fish such as salmon, halibut, etc., consume 1-2 times a week. Supplementation with fish oil, a rich source of omega-3, should include docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA). Follow dosage recommendations manufacturers.